For the prevention of delayed nausea and vomiting associated with highly and moderately emetogenic chemotherapy (HEC and MEC)
5-HT3, 5-hydroxytryptamine-3 (serotonin); HEC, highly emetogenic chemotherapy; MEC, moderately emetogenic chemotherapy; RA, receptor antagonist.
Interaction with CYP2D6 substrates with a narrow therapeutic index
Reference: 1. VARUBI [package insert]. Waltham, MA: TESARO, Inc.; 2015.